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Pharmacogenomics Background

Pharmacogenomics – the Promise of Personalized Medicine

Drug-related Adverse Reactions in the US
Drug-related adverse reactions (ADEs) constitute a significant healthcare concern in the United States. Approximately 82% of American adults consume at least one pharmaceutical while 29% utilize five or more medications.(Read more)
ADEs result in 700,000 emergency department encounters, 120,000 hospital admissions and 100,000 fatalities annually in the US. This generates over $30 billion in excess healthcare expenditures yearly. Pharmacogenomics investigations have demonstrated that over 50% of the patient population receive ineffective dosing due partly to genetic incompatibility between the patient's metabolism and the medication. Current genetic research has assisted in developing superior comprehension of this incompatibility by clarifying the importance of genetics in drug metabolism. This knowledge regarding a patient's genetic composition, combined with their lifestyle patterns and additional risk elements, improves the physician's capacity to deliver individualized medical care and treatment to each patient.
PGX Advantage Pharmacogenomics Testing
At Neugenix, we are dedicated to enhancing awareness, comprehension, and clinical application of pharmacogenomics testing. Our 17 gene PGX Advantage testing profile delivers information (Read more)
regarding the relationship between a patient's distinct genetic composition and their response to specific cardiology, pain and psychiatry medications. We recognize that as physicians, you must consistently discover methods to improve the care you deliver to each of your patients. Our pharmacogenomics examinations supply information that empowers you to provide individualized care and customized medication to satisfy your patient's distinctive requirements with favorable results.

The Testing Process

Testing Process

Impacted Medications and Genes Tested

Impacted Medications and Genes

References

  1. The Essentials of Diagnostics whitepaper. DX Insights. January 2012. National Center for Complementary and Integrative Health (NCCIH) and the Centers for Disease Control and Prevention (CDC), based on data from a special supplement—on use of complementary health approaches—to the 2012 National Health Interview Survey (NHIS).
Toxicology Services Background

Toxicology Services

Fast, reliable results for medication monitoring and substance detection.

Opioid Dependency Crisis
The CDC reports that opioid dependency is an escalating health crisis with 115 Americans dying daily from overdoses. Drug-related adverse reactions (ADEs) are a major healthcare concern.(Read more)
Around 82% of American adults take at least one medication, and 29% take five or more. ADEs lead to 700,000 ER visits, 120,000 hospital admissions, and 100,000 deaths annually — costing over $30 billion each year.
Advantage Toxicology Testing
Neugenix provides physicians with advanced tools to track adherence, diversion, and effectiveness through toxicology testing. Using urine or oral fluid specimens, TOX Advantage delivers (Read more)
crucial information on a patient's medication and substance use. This helps ensure safe prescription use, personalized care, and better treatment outcomes. We help physicians discover ways to enhance patient care through more tailored medication recommendations and treatment plans.

The Testing Process

Testing Process

Tested Analytes Within Each Drug Class

Tested Analytes

References

  1. The Essentials of Diagnostics whitepaper. DX Insights. January 2012.
  2. Pathan, Hasan, and John Williams. “Basic opioid pharmacology: an update.” British Journal of Pain vol. 6,1 (2012): 11-6.
    doi:10.1177/2049463712438493
  3. Mbughuni, Michael M et al. “Mass Spectrometry Applications for Toxicology.” EJIFCC vol. 27,4 272-287. 1 Dec. 2016.
  4. Raouf, Mena et al. “A Practical Guide to Urine Drug Monitoring.” Federal Practitioner: for the health care professionals of the VA, DoD, and PHS vol. 35,4 (2018): 38-44.
  5. Thomas G. Rosano, Patrice Y. Ohouo, Michelle Wood, Screening with Quantification for 64 Drugs and Metabolites in Human Urine using UPLC–MS-MS Analysis and a Threshold Accurate Calibration, Journal of Analytical Toxicology, Volume 41, Issue 6, July-August 2017, Pages 536–546.
    https://doi.org/10.1093/jat/bkx035

Who can Benefit from Toxicology Testing?

Toxicology examination delivers essential information and insights that regulatory authorities and healthcare professionals can utilize to establish policies and provide treatment that restricts substance exposures, diminishing the probability of adverse drug reactions and harmful health consequences.

Toxicology examinations assist physicians to:

  • Observe the patient's treatment
  • Verify suspected toxicity
  • Recognize potential risks from other medications and help prevent combined drug toxicity
  • Identify if a patient shows inadequate response
  • Track patient's adherence to treatment

Why Neugenix?

Broad Quantitative Testing

Broad Quantitative Testing

We provide precise, rapid quantitative analysis of drug metabolites in urine and oral fluids. Our testing covers over 80 analytes and metabolites, ensuring comprehensive and reliable results for every patient sample.

State-of-the-Art Technology

State-of-the-Art Technology

We utilize advanced HPLC-tandem mass spectrometry to analyze a wide range of analytes with high selectivity and sensitivity. This technology allows us to process large volumes efficiently and deliver accurate results.

Effective Quality Controls

Effective Quality Controls

Our rigorous Quality Control program minimizes the risk of errors. Every test result is thoroughly reviewed, and final reports are examined by senior scientists to ensure accuracy and reliability for clinicians.

Well-Trained Scientists

Well-Trained Scientists

Our experienced management and Ph.D. scientists handle every specimen with care. Our team is available for consultations, and our advisory board ensures we remain leaders in clinical diagnostics and healthcare innovation.

Quick Turnaround Time

Quick Turnaround Time

By leveraging the latest technology, we analyze specimens swiftly and precisely. Our high-throughput systems enable us to provide rapid, dependable turnaround times for all toxicology and pharmacogenomics testing.

Clear, Actionable Reports

Clear, Actionable Reports

Our reports are easy to interpret and clinically actionable, delivered securely via portal, fax, or EMR. Our experts are available to help physicians understand results and apply them to patient care strategies.

Exceptional Customer Service

Exceptional Customer Service

We are committed to outstanding customer service, offering tailored support to healthcare professionals. Our team ensures effective communication and helps optimize patient care at every step of the process.